U.S. President Donald Trump has called on "all nations to isolate" the Iranian government for as long as its leadership continues policies of "aggression" in the Middle East and beyond.
Speaking to world leaders at the United Nations General Assembly in New York on September 25, Trump said: "Iran's leaders sell chaos, death, and destruction. They do not respect their neighbors or borders or the sovereign rights of nations. Instead, Iran's leaders plunder the nation's resources to enrich themselves and to spread mayhem across the Middle East and far beyond."
Trump told the General Assembly: "We cannot allow the world's leading sponsor of terrorism to possess the planet's most dangerous weapons. We cannot allow a regime that chants 'death to America,' and that threatens Israel with annihilation, to possess the means to deliver a nuclear warhead to any city on earth. Just can't do it. We ask all nations to isolate Iran's regime as long as its aggression continues, and we ask all nations to support Iran's people as they struggle to reclaim their religious and righteous destiny."
Trump's criticism of Iran came in the midst of a speech that largely focused on his "America First" foreign policy, and Washington's refusal to "surrender America's sovereignty to an unelected and unaccountable global governance."
Trump praised Poland for working to make itself independent from Russian energy supplies and said that "Germany will become totally dependent on Russian energy if it does not immediately change course" on the construction of the Nord Stream 2 pipeline, which aims to deliver natural gas from Russia to Germany under the Baltic Sea.
WATCH: U.S. President Donald Trump warns Germany not to become dependent on Russian energy.
Trump also said the International Criminal Court (ICC) lacked any legitimacy and violated "all principles of justice."
"As far as America is concerned, the ICC has no jurisdiction, no legitimacy, and no authority," Trump said. "The ICC claims near-universal jurisdiction over the citizens of every country, violating all principles of justice, fairness, and due process. We will never surrender America's sovereignty to an unelected, unaccountable global bureaucracy."
On Syria's war, Trump warned that "the United States will respond if chemical weapons are deployed" by President Bashar al-Assad's forces. He said the world's "shared goals" on Syria must be de-escalation of the conflict along with a political solution that is "based on the will of the Syrian people."
He also accused the Organization of the Petroleum Exporting Countries (OPEC) "and OPEC nations" of "ripping off" the world by raising prices and said member states that receive military support from the United States will have to start sharing the cost of that defense.
Trump said that Secretary of State Mike Pompeo was heading an initiative to reevaluate U.S. foreign assistance.
"We are only going to give foreign aid to those who respect us and, frankly, are our friends," Trump told the UN gathering.
U.S. Ambassador Nikki Haley had said ahead of Trump's speech that he planned to address “the fact that we had to take on the Russian incident” in which former Russian double agent Sergei Skripal and his daughter were poisoned with the nerve agent Novichok in the English city of Salisbury in March.
But Trump made no mention of the Novichok attack in his UN speech.
Trump praised North Korean leader Kim Jong Un for "encouraging measures" since the two met in Singapore in June for a summit, thanking Kim for "his courage and steps he has taken" toward reducing tensions on the Korean peninsula.
But he said "much work needs to be done" by North Korea and that U.S. sanctions "will remain in place until denuclearization occurs."
Guterres: 'Trust Deficit'
Trump's speech to the General Assembly came after UN Secretary-General Antonio Guterres opened the weeklong event on September 25 by warning that the world was "suffering from a bad case of trust-deficit disorder."
"People are feeling troubled and insecure and trust is at a breaking point -- trust in national institutions, trust among states, trust in the rules-based world order," Guterres told the General Assembly.
"Within countries, people are losing faith in political establishments," Guterres said. "Polarization is on the rise and populism is on the march. Among countries, cooperation is less certain and more difficult and divisions in our Security Council are stark."
Urging world leaders to counteract unilateralism and rejuvenate international cooperation, Guterres sounded an alarm on issues ranging from global climate change, a growing potential for nuclear conflict, the need for all people to benefit from new technologies, and the necessity to safeguard against dangers ranging from "malicious acts in cyberspace to the weaponization of artificial intelligence."
"Today, world order is increasingly chaotic," Guterres warned. "Power relations are less clear and universal values are being eroded. Democratic principles are under siege and the rule of law is being undermined."
Guterres's grim depiction of the state of the world was the first of many speeches scheduled during the General Assembly session, which runs through October 1.
On September 25 alone, the leaders of 32 UN member states were scheduled to address the assembly.
Iranian President Hassan Rohani is due to speak later on September 25.
Iranian officials say Rohani's speech will stress that Tehran is continuing to uphold its commitments under the nuclear deal and that he will criticize the United States for breaking its international obligations under the treaty.
Hours before the session was set to begin, Trump tweeted that he had no plans to meet with Rohani on the sidelines of the gathering "despite requests" to do so.
Rohani said earlier that as a precondition for any dialogue, Trump must repair the damage done when he unilaterally withdrew the United States from Iran's 2015 nuclear deal with world powers.
"That bridge must be rebuilt," Rohani told the U.S.-based NBC news ahead of his speech.
Turkish President Recep Tayyip Erdogan's speech on September 25 is expected to focus mainly on the ongoing humanitarian crisis in Syria's northwestern province of Idlib.
Erdogan also was expected to call on the international community to share responsibility for the refugee crisis and other challenges posed by conflicts in the region.
Also due to address the General Assembly on September 25 are Kyrgyz President Sooranbai Jeenbekov; Bakir Izetbegovic, the chairman of Bosnia-Herzegovina's tripartite presidency; and Armenian Prime Minister Nikol Pashinian.